DEPO®-ESTRADIOL Contraindications

(estradiol cypionate)

CONTRAINDICATIONS

Estrogens should not be used in individuals with any of the following conditions:

1.
Undiagnosed abnormal genital bleeding.
2.
Known or suspected cancer of the breast.
3.
Known or suspected estrogen-dependent neoplasia.
4.
Active deep vein thrombosis, pulmonary embolism or history of these conditions.
5.
Active or recent (e.g., within the past year) arterial thromboembolic disease (e.g., stroke, myocardial infarction).
6.
Liver dysfunction or disease.
7.
DEPO-Estradiol should not be used in patients with known hypersensitivity to its ingredients.
8.
Known or suspected pregnancy. There is no indication for DEPO-Estradiol in pregnancy.

There appears to be little or no increased risk of birth defects in children born to women who have used estrogens and progestins from oral contraceptives inadvertently during early pregnancy. (See PRECAUTIONS.)

Find DEPO®-ESTRADIOL medical information:

Find DEPO®-ESTRADIOL medical information:

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

DEPO®-ESTRADIOL Quick Finder

Prescribing Information
Download Prescribing Information

Health Professional Information

Contraindications

CONTRAINDICATIONS

Estrogens should not be used in individuals with any of the following conditions:

1.
Undiagnosed abnormal genital bleeding.
2.
Known or suspected cancer of the breast.
3.
Known or suspected estrogen-dependent neoplasia.
4.
Active deep vein thrombosis, pulmonary embolism or history of these conditions.
5.
Active or recent (e.g., within the past year) arterial thromboembolic disease (e.g., stroke, myocardial infarction).
6.
Liver dysfunction or disease.
7.
DEPO-Estradiol should not be used in patients with known hypersensitivity to its ingredients.
8.
Known or suspected pregnancy. There is no indication for DEPO-Estradiol in pregnancy.

There appears to be little or no increased risk of birth defects in children born to women who have used estrogens and progestins from oral contraceptives inadvertently during early pregnancy. (See PRECAUTIONS.)
Medication Guide

Health Professional Information

{{section_name_patient}}

{{section_body_html_patient}}

Resources

Didn’t find what you were looking for? Contact us.

MI Digital Assistant

Chat online with Pfizer Medical Information regarding your inquiry on a Pfizer medicine.

Call 800-438-1985*

*Speak with a Pfizer Medical Information Professional regarding your medical inquiry. Available 9AM-5Pm ET Monday to Friday; excluding holidays.

Medical Inquiry

Submit a medical question for Pfizer prescription products.

Report Adverse Event

Pfizer Safety

To report an adverse event related to the Pfizer-BioNTech COVID-19 Vaccine, and you are not part of a clinical trial* for this product, click the link below to submit your information:

Pfizer Safety Reporting Site

*If you are involved in a clinical trial for this product, adverse events should be reported to your coordinating study site.

If you cannot use the above website, or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at (800) 438-1985.

FDA Medwatch

You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatch or call (800) 822-7967.