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DEMEROL Contraindications (Meperidine Hydrochloride Injection, USP)

4 CONTRAINDICATIONS

DEMEROL Injection is contraindicated in patients with:

•
Significant respiratory depression [see Warnings and Precautions (5.2)]
•
Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [see Warnings and Precautions (5.2)]
•
Concomitant use of monoamine oxidase inhibitors (MAOIs) or within 14 days of having taken an MAOI [see Warnings and Precautions (5.6), Drug Interactions (7)]
•
Known or suspected gastrointestinal obstruction, including paralytic ileus [see Warnings and Precautions (5.12)]
•
Hypersensitivity to meperidine (e.g., anaphylaxis) [see Adverse Reactions (6)]
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