Medical Information
United States
 

In order to provide you with relevant and meaningful content we need to know more about you.

Please choose the category that best describes you.

Información selecta para pacientes y cuidadores que se encuentra disponible en Español.

This content is intended for U.S. Healthcare Professionals. Would you like to proceed?

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

DEMEROL (Meperidine Hydrochloride Injection, USP)

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

DEMEROL Quick Finder

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...
Did you find an answer to your question? Yes No

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; NEONATAL OPIOID WITHDRAWAL SYNDROME; CYTOCHROME P450 3A4 INTERACTION; RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS; and MONOAMINE OXIDASE (...

Did you find an answer to your question? Yes No

1 INDICATIONS AND USAGE

DEMEROL Injection is indicated for preoperative medication, support of anesthesia, and obstetrical analgesia.

DEMEROL Injection is indicated for the management of pain severe enough to require...

Did you find an answer to your question? Yes No

2 DOSAGE AND ADMINISTRATION

2.1 Important Dosage and Administration Instructions

Use the lowest effective dosage for the shortest duration consistent with individual...

Did you find an answer to your question? Yes No

3 DOSAGE FORMS AND STRENGTHS

Injectable, Carpuject Single-dose cartridge with Luer Lock for the Carpuject Syringe System: 25 mg/mL, 50 mg/mL, 75 mg/mL, and 100 mg/mL.

Injectable, Uni-Amp unit dose pak-ampuls: 25 mg/0.5...

Did you find an answer to your question? Yes No

5 WARNINGS AND PRECAUTIONS

5.1 Addiction, Abuse, and Misuse

DEMEROL Injection contains meperidine, a Schedule II controlled substance. As an opioid, DEMEROL...

Did you find an answer to your question? Yes No

6 ADVERSE REACTIONS

The following serious adverse reactions are described, or described in greater detail, in other sections:

Did you find an answer to your question? Yes No

7 DRUG INTERACTIONS

Table 1 includes clinically significant drug interactions with DEMEROL Injection.

Table 1: Clinically Significant Drug Interactions with DEMEROL Injection...
Did you find an answer to your question? Yes No

8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

Prolonged use of opioid...

Did you find an answer to your question? Yes No

9 DRUG ABUSE AND DEPENDENCE

9.1 Controlled Substance

DEMEROL Injection contains meperidine, a Schedule II controlled substance.

...
Did you find an answer to your question? Yes No

10 OVERDOSAGE

Clinical Presentation

Acute overdose with DEMEROL Injection can be manifested by respiratory depression, somnolence...

Did you find an answer to your question? Yes No

11 DESCRIPTION

DEMEROL (meperidine hydrochloride, USP) Injection is an opioid agonist, available for intramuscular, intravenous, or subcutaneous administration. The chemical name is 4-Piperidinecarboxylic acid, 1-methyl-4-...

Did you find an answer to your question? Yes No

12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Meperidine hydrochloride is an opioid agonist with multiple actions qualitatively similar to those of morphine; the...

Did you find an answer to your question? Yes No

13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

...

Did you find an answer to your question? Yes No

16 HOW SUPPLIED/STORAGE AND HANDLING

For Parenteral Use

Solutions of DEMEROL Injection for parenteral use are clear and colorless and are available as follows:

...
Did you find an answer to your question? Yes No

17 PATIENT COUNSELING INFORMATION

Serotonin Syndrome

Inform patients that opioids could cause a rare but potentially life-threatening...

Did you find an answer to your question? Yes No

Distributed by Hospira, Inc., Lake Forest, IL 60045 USA

Logo

LAB-0846-4.0

Did you find an answer to your question? Yes No
Did you find an answer to your question? Yes No
Didn’t find what you were looking for? Contact us.
Report Adverse Event