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CYTOMEL®(liothyronine sodium)

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CYTOMEL® Quick Finder

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HIGHLIGHTS OF PRESCRIBING INFORMATION

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WARNING: NOT FOR TREATMENT OF OBESITY OR FOR WEIGHT LOSS

  • Thyroid hormones, including CYTOMEL, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss.
  • ...
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1 INDICATIONS AND USAGE

1.1 Hypothyroidism

CYTOMEL is indicated as a replacement therapy in primary (thyroidal...

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2 DOSAGE AND ADMINISTRATION

2.1 General Principles of Dosing

The dose of CYTOMEL for hypothyroidism or pituitary...

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3 DOSAGE FORMS AND STRENGTHS

Tablets (round, white to off-white) available as follows:

  • 5 mcg: debossed with KPI on one side and 115 on the other side
  • 25 mcg: scored on one side and debossed...
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5 WARNINGS AND PRECAUTIONS

5.1 Cardiac Adverse Reactions in the Elderly and in Patients with Underlying Cardiovascular Disease

...

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6 ADVERSE REACTIONS

Adverse reactions associated with CYTOMEL therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see Warnings and Precautions (5.4) and...

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7 DRUG INTERACTIONS

7.1 Drugs Known to Affect Thyroid Hormone Pharmacokinetics

Many drugs can exert effects on thyroid hormone pharmacokinetics (e.g. absorption,...

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8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

Risk Summary

Experience with...

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11 DESCRIPTION

CYTOMEL tablets contain the active ingredient, liothyronine (L-triiodothyronine or LT3), a synthetic form of a thyroid hormone liothyronine in sodium salt form. It is chemically...

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12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Thyroid hormones exert their physiologic actions through control of DNA transcription and protein synthesis....

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13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Animal studies have not been performed to evaluate the carcinogenic potential,...

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16 HOW SUPPLIED/STORAGE AND HANDLING

CYTOMEL tablets (round, white to off-white) are supplied as follows:

...
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17 PATIENT COUNSELING INFORMATION

Dosing and Administration

  • Instruct patients that CYTOMEL should only be taken as...
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This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com.

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