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Congress Materials

The information on this page pertains to select congresses, congress materials, therapeutic and disease areas. It is not intended to serve as a comprehensive overview of all congresses, congress materials, therapeutic and disease areas.
Congress materials may include information for which the product is not approved and/or inconsistent with the product uses described in the Prescribing Information. Pfizer does not suggest or recommend the use of Pfizer Products in any manner other than as described in the Prescribing Information.
Oral Presentation
Modupe Idowu; Thinh Nguyen; Erin Buckley; Rowan Brothers; Kobina Dufu; Eleanor Lisbon December 10, 2022 ASH 2022 Sickle Cell Disease

Pharmacodynamic Results From Phase 1 Studies Of GBT021601, A Next-Generation Hbs Polymerization Inhibitor For Treatment Of Sickle Cell Disease.

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Poster
Melanie E. Fields, Kaitlin L. Strumph, Manus J. Donahue, Mark Davis, Cesar Cisneros, Stephanie Bell, David Purdie, Emily Meier, Allison A. King December 10, 2022 ASH 2022 Sickle Cell Disease

Trials in Progress: Two Randomized, Double-Blind, Multicenter, Placebo-Controlled Trials Investigating the Efficacy of Voxelotor on Cerebral Blood Flow and Neurocognitive Function in Patients With Sickle Cell Disease

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Poster
Nirmish Shah, Clark Brown, Biree Andemariam, Modupe Idowu, Alexander Glaros, Jeffrey Glassberg, Robert Cronin, Barbara Moehring, Carolyn Hoppe, Sandy Dixon, Deepa Manwani December 11, 2022 ASH 2022 Sickle Cell Disease

ActIVe Study: Impact of Voxelotor on Sleep Quality, Physical Activity, and Patient-Reported Outcomes

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Poster
Celeste K. Kanne, Christina Liu, Britney Hernandez, Erica Evans, Mira P. Pochron, Kobina Dufu, Vivien A. Sheehan December 11, 2022 ASH 2022 Sickle Cell Disease

GBT021601 Increases Hemoglobin and Improves Red Blood Cell Deformability Without Rebound Hyperviscosity Upon Drug Clearance in a Sickle Mouse Model

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Poster
Kobina Dufu, Donna Oksenberg, Brian E. Cathers, Carlos Munoz, Cynthia R Muller, Pedro Cabrales December 11, 2022 ASH 2022 Sickle Cell Disease

GBT021601 Prevents Microvascular Dysfunction and Improves Hypoxia-Reoxygenation–Induced Vaso-Occlusion in a Murine Model of Sickle Cell Disease

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Poster
Kobina Dufu, Donna Oksenberg, Brian E. Cathers, Carlos Munoz, Cynthia R Muller, Pedro Cabrales December 11, 2022 ASH 2022 Sickle Cell Disease

Increased Hemoglobin Affinity for Oxygen With GBT021601 Reduces Pulmonary Hypertension and Lung Vascular Inflammation in a Murine Model of Sickle Cell Disease

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Poster
Raffaella Colombatti, Carolyn Hoppe, Elliott Vichinsky, Mona Handy, Adeseye Michael Akinsete, Mark Davis, Halima Bello-Manga, Iheanyi Okpala, Ana Christina Silva Pinto, Adlette Inati December 11, 2022 ASH 2022 Sickle Cell Disease

Insights into Readmissions Related to Vaso-occlusive Crises in Patients With Sickle Cell disease Across Geographic Regions

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Poster
Alka Potdar, Michael Caponegro, Onuralp Soylemez, Anupama Reddy, Karen Yu December 11, 2022 ASH 2022 Sickle Cell Disease

Investigating Gene Expression Signatures and Cell-Type Composition Changes in Sickle Cell Disease Using Whole Blood Transcriptomics

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Poster
Rowan O. Brothers, Mariam Akbar, Katherine B. Turrentine, Sydney Triplett, Tara M. Urner, Amy Tang, R. Clark Brown and Erin M. Buckley December 12, 2022 ASH 2022 Sickle Cell Disease

Cerebral Metabolic Stress Improves After Voxelotor Treatment in Pediatric Sickle Cell Disease

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Oral Presentation
Nirmish Shah; Thokozeni Lipato; Thomas Delea; Alexander Lonshteyn; Derek Weycker; Andy Nguyen; Anne Beaubrun, Ofelia Alvarez December 12, 2022 ASH 2022 Sickle Cell Disease

Real-World Effectiveness of voxelotor for the Treatment of Sickle Cell Disease: Group and Pediatric Subgroup Analyses of Effects on Transfusions,Vaso-occlusive Crises, and Hospitalizations

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