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CLINDAMYCIN Palmitate Hydrochloride Oral Solution (GREENSTONE LLC)

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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

CLINDAMYCIN Palmitate Hydrochloride Oral Solution (GREENSTONE LLC) Quick Finder

WARNING

Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin and may range in severity from mild diarrhea to...

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INDICATIONS AND USAGE

Clindamycin palmitate HCl is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria.

Clindamycin is also indicated in the treatment of serious infections due to...

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DOSAGE AND ADMINISTRATION

If significant diarrhea occurs during therapy, this antibiotic should be discontinued (see

Reconstitution Instructions

When reconstituted with water as...

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CONTRAINDICATIONS

This drug is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.

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WARNINGS

See

Clostridium difficile Associated Diarrhea

Clostridium difficile associated diarrhea (CDAD) has been reported...

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ADVERSE REACTIONS

The following reactions have been reported with the use of clindamycin.

Infections and Infestations

...

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OVERDOSAGE

Significant mortality was observed in mice at an intravenous dose of 855 mg/kg and in rats at an oral or subcutaneous dose of approximately 2618 mg/kg. In the mice, convulsions and depression were observed....

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DESCRIPTION

Clindamycin palmitate hydrochloride is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R...

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CLINICAL PHARMACOLOGY

Human Pharmacology

Absorption

Blood level studies comparing clindamycin palmitate HCl...

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References

  1. Smith RB, Phillips JP: Evaluation of CLEOCIN HCl and CLEOCIN Phosphate in an Aged Population. Upjohn TR 8147-82-9122-021, December 1982.
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HOW SUPPLIED

Clindamycin palmitate HCl pediatric flavored granules for oral solution is available in bottles of 100 mL (NDC 59762-0016-1).

When reconstituted as directed, each bottle yields a solution containing 75 mg...

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of clindamycin palmitate HCl and other antibacterial drugs, clindamycin palmitate HCl should...

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