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CELONTIN®(methsuximide)

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CELONTIN® Quick Finder

INDICATIONS AND USAGE

Celontin is indicated for the control of absence (petit mal) seizures that are refractory to other drugs.

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DOSAGE AND ADMINISTRATION

Optimum dosage of Celontin must be determined by trial. A suggested dosage schedule is 300 mg per day for the first week. If required, dosage may be increased thereafter at weekly intervals by 300...

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CONTRAINDICATIONS

Methsuximide should not be used in patients with a history of hypersensitivity to succinimides.

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WARNINGS

Blood dyscrasias

Blood dyscrasias, including some with fatal outcome, have been reported to be associated with the use of succinimides; therefore, periodic...

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ADVERSE REACTIONS

Gastrointestinal System: Gastrointestinal symptoms occur frequently and have included nausea or vomiting, anorexia, diarrhea, weight loss, epigastric and abdominal pain, and...

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OVERDOSAGE

Acute overdoses may produce nausea, vomiting, and CNS depression including coma with respiratory depression. Methsuximide poisoning may follow a biphasic course. Following an initial comatose state, patients have...

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DESCRIPTION

Celontin (methsuximide) is an anticonvulsant succinimide, chemically designated as N,2-Dimethyl-2-phenylsuccinimide, with the following structural formula:

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CLINICAL PHARMACOLOGY

Methsuximide suppresses the paroxysmal three cycle per second spike and wave activity associated with lapses of consciousness which is common in absence (petit mal) seizures. The frequency of...

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HOW SUPPLIED

N 0071-0525-24 (P-D 525)–Celontin Capsules, #1 capsule each containing 300 mg methsuximide; bottles of 100.

Store...

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MEDICATION GUIDE

CELONTIN (Suh lŏn' tĭn)
(methsuximide)

Capsules

Read this Medication Guide before you start taking CELONTIN and each time you get a refill...

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Company Logo

LAB-0156-6.0
November 2013

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