Medical Information
United States
 

In order to provide you with relevant and meaningful content we need to know more about you.

Please choose the category that best describes you.

Información selecta para pacientes y cuidadores que se encuentra disponible en Español.

This content is intended for U.S. Healthcare Professionals. Would you like to proceed?

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.
Not a healthcare professional? Go to the patient or caregiver website.

CAVERJECT® IMPULSE (alprostadil)

If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.

Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

CAVERJECT® IMPULSE Quick Finder

HIGHLIGHTS OF PRESCRIBING INFORMATION

These highlights do not include all the...
Did you find an answer to your question? Yes No

1 INDICATIONS AND USAGE

1.1 Erectile Dysfunction

CAVERJECT IMPULSE is indicated for the treatment of erectile dysfunction.

...
Did you find an answer to your question? Yes No

2 DOSAGE AND ADMINISTRATION

2.1 Dosage and Administration Information Overview

  • Determine the most suitable dose and formulation of CAVERJECT (CAVERJECT IMPULSE...
Did you find an answer to your question? Yes No

3 DOSAGE FORMS AND STRENGTHS

Caverject Impulse (alprostadil) for injection contains sterile, freeze-dried alprostadil for reconstitution and sterile bacteriostatic water in a prefilled dual chamber glass cartridge. It is...

Did you find an answer to your question? Yes No

4 CONTRAINDICATIONS

CAVERJECT IMPULSE should not be used:

Did you find an answer to your question? Yes No

5 WARNINGS AND PRECAUTIONS

5.1 Prolonged Erection and Priapism

Prolonged erection defined as erection lasting between 4 to 6 hours in duration occurred in 4% of 1,861...

Did you find an answer to your question? Yes No

6 ADVERSE REACTIONS

The following are discussed in more detail in other sections of the labeling:

  • Prolonged Erection and Priapism [see

    6.1 Clinical Trials Experience

    ...
Did you find an answer to your question? Yes No

7 DRUG INTERACTIONS

The potential for pharmacokinetic drug-drug interactions between alprostadil and other agents administered orally or intracavernosally has not been formally studied [see...

Did you find an answer to your question? Yes No

8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy

CAVERJECT IMPULSE is not indicated for use in females.

8.2...

Did you find an answer to your question? Yes No

10 OVERDOSAGE

Overdosage was not observed in clinical trials with CAVERJECT IMPULSE. If intracavernous overdose of CAVERJECT IMPULSE occurs, the patient should be under medical supervision until any systemic effects have...

Did you find an answer to your question? Yes No

11 DESCRIPTION

CAVERJECT IMPULSE contains alprostadil a synthetic form of prostaglandin E1 (PGE1) and is designated chemically as (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-...

Did you find an answer to your question? Yes No

12 CLINICAL PHARMACOLOGY

12.1 Mechanism of Action

Alprostadil induces erection by relaxation of trabecular smooth muscle and by dilation of cavernosal arteries. This...

Did you find an answer to your question? Yes No

13 NONCLINICAL TOXICOLOGY

13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Long-term carcinogenicity studies have not been conducted. The following battery...

Did you find an answer to your question? Yes No

14 CLINICAL STUDIES

The efficacy of CAVERJECT Sterile Powder was investigated in men with a diagnosis of erectile dysfunction due to psychogenic, vasculogenic, neurogenic, and/or mixed etiology in two double-blind placebo...

Did you find an answer to your question? Yes No

16 HOW SUPPLIED/STORAGE AND HANDLING

CAVERJECT IMPULSE is supplied as a disposable, single-dose, dual chamber syringe system. The system includes a glass cartridge, which contains sterile, freeze-dried alprostadil in the...

Did you find an answer to your question? Yes No

17 PATIENT COUNSELING INFORMATION

Advise the patient to read the FDA-approved patient labeling (Patient Information and Instructions for Use)

...

Did you find an answer to your question? Yes No

INSTRUCTIONS FOR USE

Before you use CAVERJECT, your doctor must train you in how to prepare and give the injection properly.

Before using CAVERJECT, talk to your doctor about what to expect...

Did you find an answer to your question? Yes No

This product's label may have been updated. For current full prescribing information, please visit www.pfizer.com

...

Did you find an answer to your question? Yes No
Did you find an answer to your question? Yes No
Didn’t find what you were looking for? Contact us.
Report Adverse Event