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calcium chloride injection, USP - ANYSYR Adverse Reactions


The following serious adverse reactions are also described elsewhere in the labeling:

End-Organ Damage due to Intravascular Ceftriaxone-Calcium Precipitates [see Warnings and Precautions (5.1)]
Hypotension, Bradycardia, Arrhythmias, and Syncope with Rapid Administration [see Warnings and Precautions (5.2)]
Arrhythmias with Concomitant Digoxin Use [see Warnings and Precautions (5.3)]
Tissue Necrosis and Calcinosis [see Warnings and Precautions (5.4)]
Aluminum toxicity [see Warnings and Precautions (5.5)]

The following adverse reactions have been identified in literature and postmarketing reports of calcium chloride. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure:

Nervous system disorders: Paraesthesia (upon rapid injection), calcium taste
General disorders and administration site conditions: Sense of oppression, sense of “heat wave”, local burning sensation, injection site extravasation, injection site reactions
Cardiovascular disorders: Peripheral vasodilatation, decreased blood pressure
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