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CALAN® SR (verapamil sustained release oral caplets)

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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.

CALAN® SR Quick Finder

INDICATIONS AND USAGE

CALAN SR is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial...

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DOSAGE AND ADMINISTRATION

Essential hypertension

The dose of CALAN SR should be individualized by titration and the drug should be administered with food. Initiate...

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CONTRAINDICATIONS

Verapamil HCl extended-release tablets are contraindicated in:

  1. Severe left ventricular dysfunction (see WARNINGS)
  2. ...
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WARNINGS

Heart failure

Verapamil has a negative inotropic effect, which in most patients is compensated by its afterload reduction (decreased systemic vascular...

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ADVERSE REACTIONS

Serious adverse reactions are uncommon when verapamil therapy is initiated with upward dose titration within the recommended single and total daily dose. See

Treatment of acute...

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OVERDOSAGE

Overdose with verapamil may lead to pronounced hypotension, bradycardia, and conduction system abnormalities (eg, junctional rhythm with AV dissociation and high degree AV block, including asystole). Other...

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DESCRIPTION

CALAN SR (verapamil hydrochloride) is a calcium ion influx inhibitor (slow-channel blocker or calcium ion antagonist). CALAN SR is available for oral administration as light green, capsule-shaped, scored, film-...

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CLINICAL PHARMACOLOGY

CALAN (verapamil HCl) is a calcium ion influx inhibitor (slow-channel blocker or calcium ion antagonist) that exerts its pharmacologic effects by modulating the influx of ionic calcium across the cell...

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HOW SUPPLIED

CALAN SR 120 mg extended-release tablets are light violet, oval, film coated, with CALAN debossed on one side and SR 120 on the other, supplied as:

...
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LAB-0268-13.0
Revised March 2020

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