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butorphanol tartrate injection, USP

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butorphanol tartrate injection, USP Quick Finder

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; NEONATAL OPIOID WITHDRAWAL SYNDROME; and RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

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INDICATIONS AND USAGE

Butorphanol Tartrate Injection is indicated

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as a preoperative or pre-anesthetic medication
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as a supplement to balanced anesthesia
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for the...
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DOSAGE AND ADMINISTRATION

Important Dosage and Administration Instructions

Use the lowest effective dosage for the shortest duration consistent with individual patient...

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CONTRAINDICATIONS

Butorphanol Tartrate Injection is contraindicated in:

  • Patients with significant respiratory depression (see WARNINGS)
  • Patients with...
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WARNINGS

Addiction, Abuse, and Misuse

Butorphanol tartrate injection is a Schedule IV controlled substance. As an opioid, butorphanol tartrate exposes users to the...

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ADVERSE REACTIONS

Clinical Trial Experience

A total of 1658 patients were studied in premarketing clinical trials of Butorphanol Tartrate Injection. In nearly all...

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DRUG ABUSE AND DEPENDENCE

Controlled Substance

Butorphanol Tartrate Injection contains butorphanol, a Schedule IV controlled substance.

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OVERDOSAGE

Clinical Presentation

Acute overdose with butorphanol tartrate can be manifested by respiratory depression, somnolence progressing to stupor or coma,...

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DESCRIPTION

Butorphanol tartrate is a synthetically derived opioid agonist-antagonist analgesic of the phenanthrene series. The chemical name is (-)-17-(cyclobutylmethyl) morphinan-3, 14-diol D-(-)- tartrate (1:1) (salt)....

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CLINICAL PHARMACOLOGY

Mechanism of Action

Butorphanol is a partial opioid agonist at the mu opioid receptor and a full agonist at the kappa opioid receptor. The...

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HOW SUPPLIED

Butorphanol Tartrate Injection, USP is supplied as follows:

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Distributed by Hospira Inc., Lake Forest, IL 60045 USA

LAB-0831-4.0...

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