Buprenorphine hydrochloride is contraindicated in patients with:
- Significant respiratory depression [see WARNINGS].
- Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [see WARNINGS].
- Known or suspected gastrointestinal obstruction, including paralytic ileus [see WARNINGS].
- Hypersensitivity to buprenorphine (e.g., anaphylaxis) or any other ingredient in buprenorphine hydrochloride [see WARNINGS].