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buprenorphine Hydrochloride Injection

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buprenorphine Hydrochloride Injection Quick Finder

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; NEONATAL OPIOID WITHDRAWAL SYNDROME and RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

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INDICATIONS AND USAGE

Buprenorphine hydrochloride injection is indicated for the management of pain severe enough to require an opioid analgesic and for which alternate treatments are inadequate.

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DOSAGE AND ADMINISTRATION

Use the lowest effective dosage for the shortest duration consistent with individual patients treatment goals [see

Dosing

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CONTRAINDICATIONS

Buprenorphine hydrochloride is contraindicated in patients with:

  • Significant respiratory depression [see WARNINGS].
  • Acute or...
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WARNINGS

Addiction, Abuse, and Misuse

Buprenorphine hydrochloride contains buprenorphine, a Schedule III controlled substance. As an opioid, buprenorphine...

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ADVERSE REACTIONS

The most frequent side effect in clinical studies involving 1,133 patients was sedation which occurred in approximately two-thirds of the patients. Although sedated, these patients could easily be aroused...

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DRUG ABUSE AND DEPENDENCE

Controlled Substance

Buprenorphine hydrochloride contains buprenorphine, a Schedule III controlled substance.

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OVERDOSAGE

Clinical Presentation

Acute overdose with buprenorphine hydrochloride can be manifested by respiratory depression, somnolence progressing to stupor or coma,...

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DESCRIPTION

Buprenorphine hydrochloride is a partial opioid agonist.

The chemical name of buprenorphine hydrochloride is 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy 18,19-dihydro-3-hydroxy-6-methoxy-α-methyl...

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CLINICAL PHARMACOLOGY

Mechanism of Action

Buprenorphine is a partial agonist at the mµ-opioid receptor and an antagonist at the kappa-opioid receptor. One unusual...

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HOW SUPPLIED

Unit of Sale...
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Instructions for Use of the Syringe Systems

Instructions for using the Carpuject™ Syringe are available with the reusable Carpuject™ Holder, List 2049-02.

Carpuject™ Single-dose cartridges are to be used ONLY with...

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