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BICILLIN® C-R (penicillin G benzathine, penicillin G procaine)

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BICILLIN® C-R Quick Finder

WARNING: NOT FOR INTRAVENOUS USE. DO NOT INJECT INTRAVENOUSLY OR ADMIX WITH OTHER INTRAVENOUS SOLUTIONS. THERE HAVE BEEN REPORTS OF INADVERTENT INTRAVENOUS ADMINISTRATION OF PENICILLIN G BENZATHINE WHICH HAS BEEN ASSOCIATED WITH...

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INDICATIONS AND USAGE

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bicillin C-R and other antibacterial drugs, Bicillin C-R should be used only to treat or prevent infections that...

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DOSAGE AND ADMINISTRATION

Streptococcal Infections Group A

Infections of the upper-respiratory tract, skin and soft-tissue infections, scarlet fever, and erysipelas....

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CONTRAINDICATIONS

A previous hypersensitivity reaction to any penicillin or to procaine is a contraindication.

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WARNINGS

WARNING: NOT FOR INTRAVENOUS USE. DO NOT...
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ADVERSE REACTIONS

As with other penicillins, untoward reactions of the sensitivity phenomena are likely to occur, particularly in individuals who have previously demonstrated hypersensitivity to penicillins or in those with a...

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OVERDOSAGE

Penicillin in overdosage has the potential to cause neuromuscular hyperirritability or convulsive seizures.

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DESCRIPTION

Bicillin C-R (penicillin G benzathine and penicillin G procaine injectable suspension) contains equal amounts of the benzathine and procaine salts of penicillin G. It is available for deep intramuscular injection...

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CLINICAL PHARMACOLOGY

General

Penicillin G benzathine and penicillin G procaine have a low solubility and, thus, the drugs are slowly released from intramuscular...

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REFERENCES

  1. SHAW, E.: Transverse myelitis from injection of penicillin. Am. J. Dis. Child., 111:548, 1966.
  2. KNOWLES, J.: Accidental intra-arterial injection of penicillin....
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HOW SUPPLIED

Bicillin C-R (penicillin G benzathine and penicillin G procaine injectable suspension) is supplied in packages of 10 disposable syringes as follows:

2 mL size, containing 1,200,000 units per syringe (21...

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bicillin C-R and other antibacterial drugs, Bicillin C-R should be used only to treat or...

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