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ANTIVENIN®(micrurus fulvius)
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Our scientific content is evidence-based, scientifically balanced and non-promotional. It undergoes rigorous internal medical review and is updated regularly to reflect new information.
ANTIVENIN® Quick Finder
Highlights
Indications and Usage
1 INDICATIONS AND USAGE
North American Coral Snake Antivenin (Equine) is indicated only for the treatment of envenomation caused by bites of North American coral snakes - Micrurus (including the...
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Dosage and Administration
2 DOSAGE AND ADMINISTRATION
For intravenous use only.
2.1 Dose
- Contents of each reconstituted vial can neutralize...
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Dosage Forms and Strengths
3 DOSAGE FORMS AND STRENGTHS
Each package contains one single use vial with lyophilized North American Coral Snake Antivenin (Equine) for dilution with 10 mL of diluent (Sterile Water for Injection, USP). Contents of each...
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Contraindications
4 CONTRAINDICATIONS
- Do not administer North American Coral Snake Antivenin (Equine) prophylactically to asymptomatic patients.1
- Do not administer North American Coral Snake Antivenin (...
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Warnings and Precautions
5 WARNINGS AND PRECAUTIONS
5.1 Hypersensitivity Reactions
Patients sensitive to North American Coral Snake Antivenin (Equine) or horse serum may develop anaphylaxis....
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Adverse Reactions
6 ADVERSE REACTIONS
The most common adverse reactions observed after treatment with North American Coral Snake Antivenin (Equine) were anaphylaxis and serum sickness, vomiting, and abdominal pain. Because these reactions...
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Use in Specific Populations
8 USE IN SPECIFIC POPULATIONS
8.1 Pregnancy
Risk Summary
There are no available...
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Description
11 DESCRIPTION
North American Coral Snake Antivenin (Equine) is a sterile lyophilized powder for solution for injection containing serum globulins obtained by fractionating blood from healthy horses that have been immunized...
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Clinical Pharmacology
...
12 CLINICAL PHARMACOLOGY
12.1 Mechanism of Action
North American Coral Snake Antivenin (Equine) specifically binds to and neutralizes coral snake venom.
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Clinical Studies
14 CLINICAL STUDIES
There have been no well-controlled clinical studies of the use of North American Coral Snake Antivenin (Equine) in patients experiencing envenomation by the Eastern Coral Snake, however a retrospective...
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References
15 REFERENCES
- Bowden, C and Krenzelok, E: Clinical applications of commonly used contemporary antidotes, a US perspective. Drug Safety 1997; 16(1):9-47.
- Sasaki, J et al: Coral snake bites and envenomation in...
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How Supplied/Storage and Handling
16 HOW SUPPLIED/STORAGE AND HANDLING
North American Coral Snake Antivenin (Equine) is supplied as a sterile lyophilized powder in single use vial (NDC 0008-0423-01) in a carton (NDC 0008-0423-03).
...
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Patient Counseling Information
17 PATIENT COUNSELING INFORMATION
Advise patients to contact the physician or emergency department immediately if they experience any signs and symptoms of delayed allergic reactions or serum sickness up to 14 days following...
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Report Adverse Event
To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY®, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID™ (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information:
*If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site.
If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at(800) 438-1985.
You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at www.fda.gov/medwatchor by calling
(800)-332-1088.
(800)-332-1088.