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acetylcysteine solution, USP

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acetylcysteine solution, USP Quick Finder

INDICATIONS AND USAGE

Acetylcysteine is indicated as adjuvant therapy for patients with abnormal, viscid, or inspissated mucous secretions in such conditions as:

Chronic bronchopulmonary...

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DOSAGE AND ADMINISTRATION

General

Acetylcysteine Solution 10% and 20% is available in glass vials...

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CONTRAINDICATIONS

Acetylcysteine is contraindicated in those patients who are sensitive to it.


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WARNINGS

After proper administration of acetylcysteine, an increased volume of liquified bronchial secretions may occur. When cough is inadequate, the...

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ADVERSE REACTIONS

Adverse effects have included stomatitis, nausea, vomiting, fever, rhinorrhea, drowsiness, clamminess, chest tightness, and bronchoconstriction. Clinically overt acetylcysteine...

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DESCRIPTION

Acetylcysteine solution is for inhalation (mucolytic agent) or oral administration (acetaminophen antidote), and available as sterile, unpreserved solutions (not for injection).

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CLINICAL PHARMACOLOGY

The viscosity of pulmonary mucous secretions depends on the concentrations of mucoprotein and to a lesser extent deoxyribonucleic acid (DNA). The latter increases with...

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REFERENCES

1.
Bonanomi L, Gazzaniga A. Toxicological, pharmacokinetic and metabolic studies on acetylcysteine. Eur J Respir Dis 1981; 61(suppl 111):45−51.
2....
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HOW SUPPLIED

Acetylcysteine Solution, USP is supplied in teartop vials as follows:

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WARNING: NOT FOR INJECTION

Rx only...

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