BEQVEZ™ Drug Interactions

(fidanacogene elaparvovec-dzkt)

7 DRUG INTERACTIONS

No interaction studies have been performed.

The use of BEQVEZ in patients receiving hepatotoxic medication or using hepatotoxic substances is limited. Use of hepatotoxic medications or substances may reduce the efficacy of BEQVEZ, and the risk of serious hepatic reactions may increase following administration.

Prior to BEQVEZ administration, review the patient’s existing medications to determine if they should be modified to prevent anticipated interactions described in this section.

Monitor concomitant medications after BEQVEZ administration and evaluate the need to change concomitant medications based on patient’s hepatic status and risk.

Vaccinations

Prior to BEQVEZ infusion, ensure patients are up to date on their vaccinations. If concomitant corticosteroid administration is needed following BEQVEZ infusion, delay administration of live vaccines until the patient has been weaned off corticosteroids [see Dosage and Administration (2.3)].

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Health Professional Information

Drug Interactions

7 DRUG INTERACTIONS

No interaction studies have been performed.

The use of BEQVEZ in patients receiving hepatotoxic medication or using hepatotoxic substances is limited. Use of hepatotoxic medications or substances may reduce the efficacy of BEQVEZ, and the risk of serious hepatic reactions may increase following administration.

Prior to BEQVEZ administration, review the patient’s existing medications to determine if they should be modified to prevent anticipated interactions described in this section.

Monitor concomitant medications after BEQVEZ administration and evaluate the need to change concomitant medications based on patient’s hepatic status and risk.

Vaccinations

Prior to BEQVEZ infusion, ensure patients are up to date on their vaccinations. If concomitant corticosteroid administration is needed following BEQVEZ infusion, delay administration of live vaccines until the patient has been weaned off corticosteroids [see Dosage and Administration (2.3)].

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Health Professional Information

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